Article
DNA double strand break production and rejoining in V79 cells irradiated with light ions.
Advances in space research : the official journal of the Committee on Space Research (COSPAR) - 1 Jan 1996
Belli M, Ianzini F, Sapora O, Tabocchini M A, Cera F, Cherubini R, Haque A M, Moschini G, Tiveron P, Simone G
Abstract excerpt
Low energy protons and other densely ionizing light ions are known to have RBE>1 for cellular end points relevant for stochastic and deterministic effects. The occurrence of a close relationship between them and induction of DNA dsb is still a matter of debate. We studied the production of DNA dsb in V79 cells irradiated with low energy protons having LET values ranging from 11 to 31 keV/micrometer, i.e. in the...
Topics
- Alpha Particles
- Animals
- Cell Line
- Cell Survival
- Cricetinae
- DNA
- DNA Damage
- DNA Repair
- Dose-Response Relationship, Radiation
- Ions
- Linear Energy Transfer
- Mutation
- Neutrons
- Particle Accelerators