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Optochin Resistance inStreptococcus pneumoniae:Mechanism, Significance, and Clinical Implications

1 Sept 2001

Abstract excerpt

Traditionally, Streptococcus pneumoniae is identified in the laboratory by demonstrating susceptibility to optochin. Between 1992 and 1998, 4 pneumococcal isolates exhibiting optochin resistance were recovered from patients at Children's National Medical Center. Three of the 4 isolates consisted of mixed populations of optochin-resistant and -susceptible organisms. Both subpopulations had identical antibiograms,...

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PMID: 11474432
DOI: 10.1086/322803

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