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Influence of Prior Meningococcal C Polysaccharide Vaccination on the Response and Generation of Memory after Meningococcal C Conjugate Vaccination in Young Children

1 Aug 2001

Abstract excerpt

To determine whether the immunological hyporesponsiveness induced by meningococcal AC polysaccharide (MACP) vaccines can be overcome by meningococcal C conjugate (MCC) vaccine in young children, serum bactericidal antibody (SBA) serogroup C-specific IgG and IgG avidity indices were measured in young children who received MACP vaccine, followed 7 months later by MCC vaccine, and their responses were compared with...

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PMID: 11443568
DOI: 10.1086/322024

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