Article
Kinetics of the AHL regulatory system in a model biofilm system: how many bacteria constitute a "quorum"?
Journal of molecular biology - 8 Jun 2001
Nilsson P, Olofsson A, Fagerlind M, Fagerström T, Rice S, Kjelleberg S, Steinberg P
Abstract excerpt
Acylated homoserine lactones (AHLs) regulate a wide variety of phenotypes in Gram-negative bacteria. Most research suggests that AHL-mediated phenotypes are not expressed in populations until late logarithmic phase or stationary phase. Here, we model how the concentration of AHLs inside bacterial cells and in a biofilm changes over time as a function of population growth rate, diffusion of AHLs and the rate of...
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