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Article

Mutations in the connexin26/GJB2 gene are the most common event in non-syndromic hearing loss among the German population.

Human mutation - 1 Jun 2001

Gabriel H, Kupsch P, Sudendey J, Winterhager E, Jahnke K, Lautermann J

Abstract excerpt

Congenital sensorineural hearing loss affects approximately 1/1,000 live births. Mutations in the gene encoding connexin26 (GJB2) have been described as a major cause of genetic nonsyndromic hearing impairment. Additionally, another gap junction gene, connexin30 (GJB6), was found to be responsible for hereditary hearing loss. We have studied 134 patients with severe to profound hearing loss or deafness and 13...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11385713
DOI: 10.1002/humu.1138

Genes

GJB2
GJB6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutations in the connexin26/GJB2 gene are the most common event in non-syndromic hearing loss among the German population.PMID 11385713Read ↗

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