Article
Is antigen presentation the primary function of HLA-G?
Microbes and infection - 1 Apr 2001
Le Bouteiller P, Solier C
Abstract excerpt
Human histocompatibility leukocyte antigen (HLA)-G is an antigen-presenting molecule. This review discusses the possibility that this might not be its primary function. HLA-G indeed modulates innate immunity by interacting with immunoglobulin-like receptors and by regulating HLA-E expression and its subsequent interaction with CD94/NKG2 receptors. HLA-G also down-modulates both CD8(+) and CD4(+) T-cell...
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