Article
New mutations in exon 28 of the von Willebrand factor gene detected in patients with different types of von Willebrand's disease.
Haematologica - 1 Apr 2001
Casaña P, Martínez F, Haya S, Tavares A, Aznar J A
Abstract excerpt
BACKGROUND AND OBJECTIVES: von Willebrand's disease (vWD), the most common hereditary bleeding disorder in humans, is caused by qualitative and/or quantitative deficiencies of von Willebrand factor, and can manifest itself under several different phenotypes. Most of the molecular defects have been detected in qualitative variants involving exon 28 of the vWF gene. Patients from four unrelated families with...
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