Article
Vrp1p functions in both actomyosin ring-dependent and Hof1p-dependent pathways of cytokinesis.
Traffic (Copenhagen, Denmark) - 1 Mar 2001
Naqvi S N, Feng Q, Boulton V J, Zahn R, Munn A L
Abstract excerpt
Vrp1p/verprolin/End5p is a Saccharomyces cerevisiae proline-rich protein, structurally and functionally related to human Wiskott-Aldrich syndrome protein-interacting protein. Vrp1p is required for viability at 37 degrees C, but not 24 degrees C. Here, we show that loss of Vrp1p (vrp1Delta) leads to a 3-4-fold delay in cytokinesis, wide bud necks, abnormal actomyosin rings, and aberrant septa even at 24 degrees C....
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