Article
Use of genotypic resistance testing to guide hiv therapy: clinical impact and cost-effectiveness.
Annals of internal medicine - 20 Mar 2001
Weinstein M C, Goldie S J, Losina E, Cohen C J, Baxter J D, Zhang H, Kimmel A D, Freedberg K A
Abstract excerpt
BACKGROUND: Genotypic sequencing for drug-resistant strains of HIV can guide the choice of antiretroviral therapy. OBJECTIVE: To assess the cost-effectiveness of genotypic resistance testing for patients acquiring drug resistance through failed treatment (secondary resistance) and those infected with resistant virus (primary resistance). DESIGN: Cost-effectiveness analysis with an HIV simulation model...
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