Article
Clinical expression and SRY gene analysis in XY subjects lacking gonadal tissue.
American journal of medical genetics - 15 Mar 2001
Zenteno J C, Jiménez A L, Canto P, Valdéz H, Méndez J P, Kofman-Alfaro S
Abstract excerpt
In several syndromes genetic males lack gonadal tissue. A range of phenotypes are seen, which varies from complete female external genitalia to anorchic subjects with sexual infantilism. Differences in phenotypic expression depend on the stage at which testes degenerated during intrauterine development. Although most cases of these syndromes are sporadic, several instances of familial recurrence suggest a genetic...
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