Article
Evolution of bacterial pathogenesis.
Cellular and molecular life sciences : CMLS - 30 Nov 1999
Ziebuhr W, Ohlsen K, Karch H, Korhonen T, Hacker J
Abstract excerpt
The evolution of bacteria is associated with continuous generation of novel genetic variants. The major driving forces in this process are point mutations, genetic rearrangements, and horizontal gene transfer. A large number of human and animal bacterial pathogens have evolved the capacity to produce virulence factors that are directly involved in infection and disease. Additionally, many bacteria express...
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