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Article

Pathogenetic mechanisms of atopic dermatitis.

Archivum immunologiae et therapiae experimentalis - 1 Jan 2000

Pastore S, Mascia F, Giustizieri M L, Giannetti A, Girolomoni G

Abstract excerpt

Atopic dermatitis (AD) is a chronic inflammatory disease which results from complex interactions between genetic and environmental mechanisms. An altered lipid composition of the stratum corneum is responsible for the xerotic aspect of the skin and determines a higher permeability to allergens and irritants. Keratinocytes of AD patients exhibit a propensity to an exaggerated production of cytokines and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 11197604

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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