Polyomavirus JC genotypes in an urban United States population reflect the history of African origin and genetic admixture in modern African Americans.

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Article

Polyomavirus JC genotypes in an urban United States population reflect the history of African origin and genetic admixture in modern African Americans.

Human biology - 1 Oct 2000

Chima S C, Ryschkewitsch C F, Fan K J, Stoner G L

Abstract excerpt

The human polyomavirus JC (JC virus), a small, circular, double-stranded DNA virus, has a worldwide distribution and is excreted harmlessly in urine by 20% to 70% of adults. DNA sequence analysis has identified seven distinct genotypes that likely coevolved with modern humans, although the mode of virus transmission is unknown. Type 1 is European in its distribution. Types 2 and 7 are Asian, while Types 3 and 6...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Black People
Child
Child, Preschool
DNA, Viral
District of Columbia
Emigration and Immigration
Female
Genetic Testing
Genetic Variation
Genome, Viral
Genotype
Humans
JC Virus
Male

Source

Open in PubMed

Identifiers

PMID: 11126728

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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