Article
Accuracy and cost-effectiveness of a new strategy to screen for celiac disease in children with Down syndrome.
The Journal of pediatrics - 1 Dec 2000
Csizmadia C G, Mearin M L, Oren A, Kromhout A, Crusius J B, von Blomberg B M, Peña A S, Wiggers M N, Vandenbroucke J P
Abstract excerpt
OBJECTIVES: To investigate the best approach to screen for celiac disease (CD) in patients with Down syndrome (DS). STUDY DESIGN: One hundred thirty-seven children with DS were followed up longitudinally. CD screening was offered in 1994, 1996, and 1999 by determination of serum immunoglobulin A-anti-endomysium antibodies (AEA). The HLA-DQA1*0501/DQB1*02 allelic combination known to be strongly positively...
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