Article
A Novel GATA Factor Transcriptionally Represses Yolk Protein Precursor Genes in the Mosquito Aedes aegypti via Interaction with the CtBP Corepressor
1 Jan 2001
Abstract excerpt
In anautogenous mosquitoes, vitellogenesis, the key event in egg maturation, requires a blood meal. Consequently, mosquitoes are vectors of many devastating human diseases. An important adaptation for anautogenicity is the previtellogenic arrest (the state of arrest) preventing the activation of the yolk protein precursor (YPP) genes Vg and VCP prior to blood feeding. A novel GATA factor (AaGATAr) that recognizes...
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