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Article

The plant isoflavenoid genistein activates p53 and Chk2 in an ATM-dependent manner.

The Journal of biological chemistry - 16 Feb 2001

Ye R, Bodero A, Zhou B B, Khanna K K, Lavin M F, Lees-Miller S P

Abstract excerpt

Genistein is an isoflavenoid that is abundant in soy beans. Genistein has been reported to have a wide range of biological activities and to play a role in the diminished incidence of breast cancer in populations that consume a soy-rich diet. Genistein was originally identified as an inhibitor of...

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Source

Identifiers

PMID: 11096068
DOI: 10.1074/jbc.M004894200

Genes

ATM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11096068-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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The plant isoflavenoid genistein activates p53 and Chk2 in an ATM-dependent manner.PMID 11096068Read ↗

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