Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Telomere Shortening With Aging in Human Liver

1 Nov 2000

Abstract excerpt

Progressive telomere shortening with aging was studied in the normal liver tissue of 94 human subjects aged between 0 and 101 years old to determine the rate of telomere loss in 1 year. Telomere length demonstrated accelerated shortening with reduction of 55 base pairs (bp) per year. The mean telomere length in five neonates was 12.9 +/- 2.6 kilobase pairs (kbp), and that in one centenarian was 8.3 kbp. Mean...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Telomeres, Telomerase, and Senescence

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 11078086
DOI: 10.1093/gerona/55.11.b533

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Telomere Shortening With Aging in Human LiverPMID 11078086Read ↗

Telomere dysfunction in chronic liver disease: The link from agingSemantic proximity Read ↗

Telomere Shortening in Chronic Liver DiseasesSemantic proximity Read ↗

Telomere Biology Disorder: A Focus on Gastrointestinal and Hepatic Manifestations.Semantic proximity Read ↗

Relationship between Telomere Maintenance and Liver DiseaseSemantic proximity Read ↗

Telomere Reduction in Human Liver Tissues with Age and Chronic InflammationSemantic proximity Read ↗

Telomere length in human liver diseasesSemantic proximity Read ↗

Telomere shortening with aging in the human pancreasSemantic proximity Read ↗

Sustained telomere length in hepatocytes and cholangiocytes with increasing age in normal liverSemantic proximity Read ↗

Accelerated telomere reduction and hepatocyte senescence in tolerated human liver allograftsSemantic proximity Read ↗

Hepatocyte telomere shortening and senescence are general markers of human liver cirrhosisSemantic proximity Read ↗

Telomeres and telomere dynamics: relevance to cancers of the GI tract.Semantic proximity Read ↗

Telomere Length in Patients with Alcohol-Associated Liver Disease: A Brief ReportSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.