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Article

Integrated analysis of sequence evolution and population history using hypervariable compound haplotypes.

Human molecular genetics - 1 Nov 2000

Rogers E J, Shone A C, Alonso S, May C A, Armour J A

Abstract excerpt

We have examined compound haplotypes from a highly informative region of human chromosome 16, in which information from the rapid evolution of a highly unstable minisatellite is integrated with data on the longer-term evolution of this segment from 10 flanking substitutional polymorphisms. Combined with sequence data from non-human primates, analysis of relationships between these compound haplotypes allows the...

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PMID: 11063726
DOI: 10.1093/hmg/9.18.2675

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