Article
Acetaldehyde production by non-pathogenicNeisseria in human oral microflora: Implications for carcinogenesis in upper aerodigestive tract
1 Jan 2000
Abstract excerpt
Many epidemiological studies have identified chronic alcohol consumption as a significant risk factor for cancer of the upper aerodigestive tract (UAT) in human. Although acetaldehyde, the first metabolite from ethanol by alcohol dehydrogenase (ADH), is regarded as a carcinogen, how systemic production of acetaldehyde particularly affects the UAT remains unclear. In our study, we searched for the regional source...
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