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Article

Role of Sertoli Cells in Injury‐Associated Testicular Germ Cell Apoptosis

1 Nov 2000

Abstract excerpt

This review examines experimental models of Sertoli cell injury resulting in germ cell apoptosis. Since germ cells exist in an environment created by Sertoli cells, paracrine signaling between these intimately associated cells must regulate the process of germ cell death. Germ cell apoptosis may be signaled by a decrease in Sertoli cell pro-survival factors, an increase in Sertoli cell pro-apoptotic factors, or...

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PMID: 11044252
DOI: 10.1111/j.1525-1373.2000.22513.x

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