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Article

Evaluation of the Roche Diagnostics LightCycler-Apo B 3500 Mutation Detection Kit.

Clinical chemistry and laboratory medicine - 1 Jul 2000

Nauck M, Wieland H, März W

Abstract excerpt

Familial defective apolipoprotein (apo) B-100 is an autosomal codominant disorder associated with hypercholesterolemia and an increased risk of coronary artery disease. Two independent mutations affecting the codon 3500 (Arg3500-->Gln and Arg3500-->Trp) have been shown to cause ligand-defective apo B-100. Identification of carriers of these mutations is an important step in the risk stratification of individuals...

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Identifiers

PMID: 11028773
DOI: 10.1515/CCLM.2000.096

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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