Article
[Immunopharmacologic properties of 12-iminosubstituted 8-aza-D-homogonan and trimezon].
Eksperimental'naia i klinicheskaia farmakologiia - 1 Jan 2000
Liubin G S, Konoplia N A, Guliakevich O V, Kuz'mitskiĭ B B
Abstract excerpt
The immunopharmacological properties of two new compounds with an 8-azasteroidal structure, representing the salts (hydrochloride and acetate) of 12-imino-substituted 8-aza-D-homogonan, were studied in comparison with the properties of the immunostimulant trimeson. Similar to trimeson, both new compounds produce a dose-dependent activation of the humoral chain of immunogenesis in the model of primary immune...
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