Article
Genotyping of alpha-antitrypsin in ten Croatian families.
Clinical biochemistry - 1 Jul 2000
Zuntar I, Topić E, Jurcić Z, Zubcić A
Abstract excerpt
OBJECTIVES: The aims of the study were to determine alpha-antitrypsin (AAT) genotype by a simple DNA-based method and to investigate the association of AAT genotype and serum AAT concentration in a group of ten families. METHODS AND RESULTS: AAT genotype was determined by PCR-RFLP and serum concentration by radial immunodiffusion in samples from each member of ten families (mother, father, and child/children). In...
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