Article
Rotavirus serotypes: classification and importance in epidemiology, immunity, and vaccine development.
Journal of health, population, and nutrition - 1 Jun 2000
Hoshino Y, Kapikian A Z
Abstract excerpt
The development and implementation of safe and effective vaccines to prevent the enormous health burden of rotavirus-associated disease is a global public health goal. Human rotaviruses, the major aetiological agents of severe infantile diarrhoea worldwide, display surprisingly diverse and complex serotypic specificities. Ten VP7 serotypes and 7 VP4 serotypes have so far been detected. An increasing number of...
Topics
- Antibodies, Viral
- Child
- Child, Preschool
- Diarrhea, Infantile
- Epitopes
- Female
- Genotype
- Humans
- Immunization
- Infant
- Infant, Newborn
- Male
