Article
Factor V Leiden mutation, prothrombin gene mutation, and deficiencies in coagulation inhibitors associated with Budd-Chiari syndrome and portal vein thrombosis: results of a case-control study.
Blood - 1 Oct 2000
Janssen H L, Meinardi J R, Vleggaar F P, van Uum S H, Haagsma E B, van Der Meer F J, van Hattum J, Chamuleau R A, Adang R P, Vandenbroucke J P, van Hoek B, Rosendaal F R
Abstract excerpt
In a collaborative multicenter case-control study, we investigated the effect of factor V Leiden mutation, prothrombin gene mutation, and inherited deficiencies of protein C, protein S, and antithrombin on the risk of Budd-Chiari syndrome (BCS) and portal vein thrombosis (PVT). We compared 43 BCS patients and 92 PVT patients with 474 population-based controls. The relative risk of BCS was 11.3 (95% CI 4.8-26.5)...
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