Article
A physician's primer to antiretroviral drug resistance testing.
The AIDS reader - 1 Aug 2000
Wilson J W, Bean P
Abstract excerpt
Evaluating the genetic composition of HIV has evolved from a traditional epidemiologic research tool into a widely used clinical asset in the management of HIV infection. Genotypic and phenotypic testing is designed to identify drugs less likely to be therapeutically effective. Genotypic assays identify specific "gene mutations" or nucleotide substitutions known to confer drug resistance, whereas phenotypic...
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