Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Screening for hemochromatosis in routine medical care: an evaluation of mean corpuscular volume and mean corpuscular hemoglobin.

Genetic testing - 1 Jan 2000

Barton J C, Bertoli L F, Rothenberg B E

Abstract excerpt

Our aim was to evaluate the potential utility of mean corpuscular volume (MCV) and mean corpuscular hemoglobin (MCH) to detect hemochromatosis. We computed the accuracy of MCV and MCH cut-off points > or = upper reference limits using data from 94 probands and 132 white controls. Our reference ranges are MCV 80.0-97.0 fL and MCH 26.0-32.0 pg. Sensitivity of MCV was 8.6-48.3% for men and 2.8-44.4% for women...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Case-Control Studies
Share to Erythrocyte Indices

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Testing

Share to Hemochromatosis

Share to Hemoglobins

Share to Predictive Value of Tests

Share to Sensitivity and Specificity

Source

Identifiers

PMID: 10953947
DOI: 10.1089/10906570050114786

Genes

HFE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Screening for hemochromatosis in routine medical care: an evaluation of mean corpuscular volume and mean corpuscular hemoglobin.PMID 10953947Read ↗

Peripheral blood erythrocyte parameters in hemochromatosis: evidence for increased erythrocyte hemoglobin content.Semantic proximity Read ↗

Mean corpuscular volume in <i>HFE</i> p.C282Y/p.H63D compound heterozygotes with high iron phenotypes: clinical and laboratory associationsSemantic proximity Read ↗

Platelet counts in HFE p.C282Y/p.C282Y and wt/wt post-screening clinical evaluation participants.Semantic proximity Read ↗

Population screening for hemochromatosis: a comparison of unbound iron-binding capacity, transferrin saturation, and C282Y genotyping in 5,211 voluntary blood donors.Semantic proximity Read ↗

Statistical haemoglobin thresholds to define anaemia across the lifecycleSemantic proximity Read ↗

Sensitivity and specificity of mean corpuscular volume testing for screening for α‐thalassemia‐1 and β‐thalassemia traitsSemantic proximity Read ↗

GWAS and PheWAS of Red Blood Cell Components in a Northern Nevadan CohortSemantic proximity Read ↗

Magnetic Resonance Liver Iron Concentration Can Guide Venesection Decision-Making in Hyperferritinemia.Semantic proximity Read ↗

Estimated analytic validity of HFE C282Y mutation testing in population screening: the potential value of confirmatory testing.Semantic proximity Read ↗

Mean corpuscular volume of heterozygotes for beta-thalassemia correlates with the severity of mutations.Semantic proximity Read ↗

Evaluation of a single-tube multiplex polymerase chain reaction screen for detection of common alpha-thalassemia genotypes in a clinical laboratory.Semantic proximity Read ↗

Population-based screening for hemochromatosis using phenotypic and DNA testing among employees of health maintenance organizations in Springfield, Missouri.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.