Article
[Surgery of hereditary colorectal carcinoma].
Zentralblatt fur Chirurgie - 1 Jan 2000
Pistorius S, Schackert H K, Nagel M, Saeger H D
Abstract excerpt
Hereditary colorectal cancer syndromes account for about 7% of all colorectal carcinomas. The most frequent form is Hereditary Nonpolyposis Colorectal Cancer (HNPCC). Identification, cloning and sequence analysis of the predisposing genes enables identification of mutation carriers and non-mutation carriers, respectively. These genetic informations can be used in an individually tailored clinical surveillance...
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