Article
Carrier detection of Duchenne/Becker muscular dystrophy by using fluorescent linkage analysis in Taiwan.
Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi - 1 Jan 2000
Lee C C, Wu M C, Wu J Y, Li T C, Tsai F J, Tsai C H
Abstract excerpt
The mutation analysis of Duchenne/Becker muscular dystrophy (DMD/BMD) is made difficult by the size and structure of the gene. The dystrophin gene deletion is responsible for 45-58% of DMD/BMD cases in Taiwan. For the others, who have no deletions, carrier detection was performed by DNA linkage analysis. To determine frequencies of each allele and heterozygosity of each short tandem repeats (STR) marker, we...
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