Article
Alcoholism susceptibility loci: confirmation studies in a replicate sample and further mapping.
Alcoholism, clinical and experimental research - 1 Jul 2000
Foroud T, Edenberg H J, Goate A, Rice J, Flury L, Koller D L, Bierut L J, Conneally P M, Nurnberger J I, Bucholz K K, Li T K, Hesselbrock V, Crowe R, Schuckit M, Porjesz B, Begleiter H, Reich T
Abstract excerpt
BACKGROUND: There is substantial evidence for a significant genetic component to the risk for alcoholism. A previous study reported linkage to chromosomes 1, 2, and 7 in a large data set that consisted of 105 families, each with at least three alcoholic members. METHODS: Additional genotyping in the 105 families has been completed in the chromosomal regions identified in the initial analyses, and a replication...
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