Article
Deconstructing Mendel: new paradigms in genetic mechanisms.
Clinical and investigative medicine. Medecine clinique et experimentale - 1 Jun 2000
Gilchrist D, Glerum D M, Wevrick R
Abstract excerpt
As knowledge of the mechanisms of genetic action expands, this new information must be incorporated into the whole. The result is that old concepts are modified or deleted or new paradigms are created. The authors review advances in the understanding of traditional and nontraditional inheritance, including genomic imprinting and mitochondrial inheritance.
Topics
- DNA, Mitochondrial
- Extrachromosomal Inheritance
- Genes
- Genetic Diseases, Inborn
- Genetics, Medical
- Genome, Human
- Genomic Imprinting
- Humans
- Mitochondrial Myopathies
- Mutation
- Neoplasms
- Penetrance