Article
Single- and multidrug resistance mutations to reverse transcriptase and protease inhibitors: human immunodeficiency virus type 1-infected patients from two geographical areas in Spain. Spanish Groups for Antiretroviral Resistance Studies.
Journal of human virology - 1 Jan 2000
Pérez-Alvarez L, Villahermosa M L, Cuevas M T, Delgado E, Manjón N, Vázquez de Parga E, Medrano L, Contreras G, Thomson M M, Colomo C, Taboada J A, Nájera R
Abstract excerpt
OBJECTIVES: To describe the prevalence of genotypic resistance mutations, including single and multidrug resistance (MDR) to reverse transcriptase (RT) and protease (PR) inhibitors in treated and untreated patients from two geographical areas in Spain (Madrid and Galicia). STUDY DESIGN/METHODS: Resistance mutations to RT inhibitors were studied by line probe assay (LiPA) or by automated sequencing in 468 patients...
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