Mild spherocytic hereditary elliptocytosis and altered levels of α- and γ-adducins in β-adducin-deficient mice

Abstract excerpt

The membrane skeleton, a dynamic network of proteins associated with the plasma membrane, determines the shape and mechanical properties of erythrocytes. Deficiencies or defects in membrane skeletal proteins are associated with inherited disorders of erythrocyte morphology and function. Adducin is one of the proteins localized at the spectrin-actin junction of the membrane skeleton. In this work we show that...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Blood properties and coagulation
• Share to Erythrocyte Function and Pathophysiology
• Share to Hemoglobinopathies and Related Disorders