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Article

emm and sof gene sequence variation in relation to serological typing of opacity-factor-positive group A streptococci.

Microbiology (Reading, England) - 1 May 2000

Beall Bernard, Gherardi Giovanni, Lovgren Marguerite, Facklam Richard R, Forwick Betty A, Tyrrell Gregory J

Abstract excerpt

Approximately 40-60% of group A streptococcal (GAS) isolates are capable of opacifying sera, due to the expression of the sof (serum opacity factor) gene. The emm (M protein gene) and sof 5' sequences were obtained from a diverse set of GAS reference strains and clinical isolates, and correlated with M serotyping and anti-opacity-factor testing results. Attempts to amplify sof from strains with M serotypes or emm...

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PMID: 10832648
DOI: 10.1099/00221287-146-5-1195

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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