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Article

Phenotypic suppression of empty spiracles is prevented by buttonhead.

Nature - 18 May 2000

Schöck F, Reischl J, Wimmer E, Taubert H, Purnell B A, Jäckle H

Abstract excerpt

Unlike the trunk segments, the anterior head segments of Drosophila are formed in the absence of pair-rule and HOX-cluster gene expression, by the activities of the gap-like genes orthodenticle (otd), empty spiracles (ems) and buttonhead (btd). The products of these genes are transcription factors, but only EMS has a HOX-like homeodomain. Indeed, ems can confer identity to trunk segments when other HOX-cluster...

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PMID: 10830964
DOI: 10.1038/35012620

Genes

BTD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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