Article
Genetic variability determinants of Helicobacter pylori: influence of clinical background and geographic origin of isolates.
The Journal of infectious diseases - 1 May 2000
Göttke M U, Fallone C A, Barkun A N, Vogt K, Loo V, Trautmann M, Tong J Z, Nguyen T N, Fainsilber T, Hahn H H, Körber J, Lowe A, Beech R N
Abstract excerpt
Helicobacter pylori has an unusual pattern of genetic variation, which complicates research on this organism. To gain a better understanding of the forces behind this phenomenon, the extent to which recombination and single point mutations affect genetic variability in H. pylori was quantified and the influence of both geographical distance and clinical background were assessed. Site-directed...
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