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Article

Recombination and clonal groupings within Helicobacter pylori from different geographical regions.

Molecular microbiology - 1 May 1999

Achtman M, Azuma T, Berg D E, Ito Y, Morelli G, Pan Z J, Suerbaum S, Thompson S A, van der Ende A, van Doorn L J

Abstract excerpt

A collection of 20 strains of Helicobacter pylori from several regions of the world was studied to better understand the population genetic structure and diversity of this species. Sequences of fragments from seven housekeeping genes (atpA, efp, mutY, ppa, trpC, ureI, yphC ) and two virulence-associated genes (cagA, vacA) showed high levels of synonymous sequence variation (mean percentage Ks of 10-27%) and lower...

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PMID: 10320570
DOI: 10.1046/j.1365-2958.1999.01382.x

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