Article
C282Y mutation in the HLA-H gene is not a risk factor for patients with myocardial infarction.
Journal of cardiovascular risk - 1 Feb 2000
Annichino-Bizzacchi J M, Saad S T, Arruda V R, Ramires J A, Siqueira L H, Chiaparini L C, Mansur A P
Abstract excerpt
BACKGROUND: Iron is suspected to play a role in the development of atherosclerosis and in the progression of the disease, and consequently in myocardial infarction. Authors of a recent study identified a mutation in HLA-H gene, C282Y, that is an excellent marker for hemochromatosis, which is the most common cause of iron overload. There is a high prevalence of carriers of heterozygous hemochromatosis, most of...
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