Article
[Neuronal expression of foreign genes with recombinant rabies virus variants].
Revue neurologique - 1 Mar 2000
Etessami R, Conzelmann K K, Marion R, Tsiang H, Ceccaldi P E
Abstract excerpt
Rabies virus variants obtained by recombinant DNA techniques enabled us to use the high neurotropism of rabies virus to express foreign genes (e.g: Chloramphenicol Acetyl Transferase gene) in neuronal cell cultures as well as in rodent brain. The foreign gene was inserted in the viral pseudogene region; this insertion did not affect the neurotropism of rabies virus, as shown by infection of neuronal cell cultures...
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