Article
Correlation between structure of Bcl-2 and its inhibitory function of JNK and caspase activity in dopaminergic neuronal apoptosis.
Journal of neurochemistry - 1 Apr 2000
Choi W S, Yoon S Y, Chang I I, Choi E J, Rhim H, Jin B K, Oh T H, Krajewski S, Reed J C, Oh Y J
Abstract excerpt
To examine the correlation between the structure of Bcl-2 and its inhibitory function of c-Jun N-terminal kinase (JNK) and caspase activity, we established a dopaminergic neuronal cell line, MN9D overexpressing Bcl-2 (MN9D/Bcl-2) or its structural mutants. The mutants comprised a point mutation i...
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