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Article

Desmoids in familial adenomatous polyposis are monoclonal proliferations

1 Feb 2000

Abstract excerpt

Desmoids are poorly-understood, locally aggressive, non-metastasizing fibromatoses that occur with disproportionate frequency in patients with familial adenomatous polyposis (FAP). Their nature is controversial with arguments for and against a neoplastic origin. Neoplastic proliferations are by definition monoclonal, whereas reactive processes originate from a polyclonal background. We examined clonality of 25...

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Identifiers

PMID: 10732754
DOI: 10.1054/bjoc.1999.1007

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