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Article

HLA class I in acute promyelocytic leukemia (APL): possible correlation with clinical outcome.

Leukemia - 1 Mar 2000

Bolognesi E, Cimino G, Diverio D, Rapanotti M C, D'Alfonso S, Fleischhauer K, Migliaretti G, Momigliano-Richiardi P

Abstract excerpt

The majority of patients with acute promyelocytic leukemia (APL) possess either a bcr1 or a bcr3 type fusion between PML and RARalpha genes. The junction sequences may possibly be a target for immune response and influence susceptibility to the disease. In this case, HLA class I allele frequencies would be different between bcr1 and bcr3 patients. To test this hypothesis, we typed 102 APL patients for HLA-A, -B...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10720132
DOI: 10.1038/sj.leu.2401691

Genes

AIDA
PML

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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