Clinical application of the Quantiplex HCV RNA 2.0 and Amplicor HCV Monitor assays for quantifying serum hepatitis C virus RNA.

doi:10.1136/jcp.52.11.807

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Article

Clinical application of the Quantiplex HCV RNA 2.0 and Amplicor HCV Monitor assays for quantifying serum hepatitis C virus RNA.

Journal of clinical pathology - 1 Nov 1999

Yu M L, Chuang W L, Chen S C, Lin Z Y, Hsieh M Y, Wang L Y, Chang W Y

Abstract excerpt

AIM: To compare the performance characteristics and clinical application of two different technologies for quantifying serum hepatitis C virus (HCV) RNA levels. METHODS: HCV RNA was quantified by Amplicor HCV Monitor assay (Amplicor) and Quantiplex HCV RNA 2.0 assay (bDNA-2) in 119 sera from 107 HCV infected patients. RESULTS: Both assays had similar sensitivity (79.4% for Amplicor; 86.0% for bDNA-2), acceptable...

Topics

Adult
Female
Genotype
Hepacivirus
Hepatitis C, Chronic
Humans
Interferon-alpha
Male
Middle Aged
RNA, Viral
Reagent Kits, Diagnostic
Reverse Transcriptase Polymerase Chain Reaction
Sensitivity and Specificity
Sex Factors

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Identifiers

PMID: 10690168
DOI: 10.1136/jcp.52.11.807
PMCID: PMC501590

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