Article
Complement component C6 polymorphism: novel protein-typing technique and distribution of allotypes in Germany.
Experimental and clinical immunogenetics - 1 Jan 2000
Schwarzenholz B, Correns A, Schröder H, Geserick G
Abstract excerpt
The genetic polymorphism of human C6 was investigated in Germany using an improved technique: polyacrylamide gel isoelectric focusing and subsequent direct immunofixation with monospecific C6 antisera. Typing of C6 was performed on native serum samples from 1,775 unrelated persons. The gene frequencies in the population study were as follows: C6*A 0.6313, C6*B 0.3566 and the rare alleles C6*R 0. 0121. In total, 8...
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