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INDUCTION OF PROTECTIVE IMMUNITY IN CHICKENS IMMUNISED WITH PLASMID DNA ENCODING INFECTIOUS BURSAL DISEASE VIRUS ANTIGENS

1 Nov 1999

Abstract excerpt

Direct DNA inoculations were used to determine the efficacy of gene immunisation of chickens to elicit protective immune responses against infectious bursal disease virus (IBDV). The vp2 gene of IBDV strains GP40 and D78, and the vp2-vp4-vp3 encoding segment of strain D78 were cloned in an expression vector which consisted of human cytomegalovirus (HCMV) immediate early enhancer and promoter, adenovirus...

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PMID: 10641338
DOI: 10.1556/avet.47.1999.4.8

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