Article
A peptide permease mutant of Mycobacterium bovis BCG resistant to the toxic peptides glutathione and S-nitrosoglutathione.
Infection and immunity - 1 Feb 2000
Green R M, Seth A, Connell N D
Abstract excerpt
Oligopeptides play important roles in bacterial nutrition and signaling. Using sequences from the available genome database for Mycobacterium tuberculosis H37Rv, the oligopeptide permease operon (oppBCDA) of Mycobacterium bovis BCG was cloned from a cosmid library. An opp mutant strain was constructed by homologous recombination with an allele of oppD interrupted by kanamycin and streptomycin resistance markers....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.