Article
Mechanism of ubiquinol oxidation by the bc(1) complex: role of the iron sulfur protein and its mobility.
Biochemistry - 30 Nov 1999
Crofts A R, Guergova-Kuras M, Huang L, Kuras R, Zhang Z, Berry E A
Abstract excerpt
Native structures of ubihydroquinone:cytochrome c oxidoreductase (bc(1) complex) from different sources, and structures with inhibitors in place, show a 16-22 A displacement of the [2Fe-2S] cluster and the position of the C-terminal extrinsic domain of the iron sulfur protein. None of the structures shows a static configuration that would allow catalysis of all partial reactions of quinol oxidation. We have...
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