Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A profile of differentially expressed genes in primary colorectal cancer using suppression subtractive hybridization

7 Dec 1999

Abstract excerpt

As a step towards understanding the complex differences between normal cells and cancer cells, we have used suppression subtractive hybridization (SSH) to generate a profile of genes overexpressed in primary colorectal cancer (CRC). From a 35¿ omitted¿000 clone SSH-cDNA repertoire, we have screened 400 random clones by reverse Northern blotting, of which 45 clones were scored as overexpressed in tumor compared to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Galectins and Cancer Biology
Share to Genetic factors in colorectal cancer
Share to TGF-β signaling in diseases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10601642
DOI: 10.1016/s0014-5793(99)01578-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A profile of differentially expressed genes in primary colorectal cancer using suppression subtractive hybridizationPMID 10601642Read ↗

Analysis of differentially expressed genes in human hepatocellular carcinoma using suppression subtractive hybridizationSemantic proximity Read ↗

RaSH, a rapid subtraction hybridization approach for identifying and cloning differentially expressed genesSemantic proximity Read ↗

Functional identification of cancer-relevant genes through large-scale RNA interference screens in mammalian cells.Semantic proximity Read ↗

Target validation for genomics using peptide‐specific phage antibodies: A study of five gene products overexpressed in colorectal cancerSemantic proximity Read ↗

Overexpression of FOXO3, MYD88, and GAPDH Identified by Suppression Subtractive Hybridization in Esophageal Cancer Is Associated with AutophagySemantic proximity Read ↗

Expression genetics in cancer: Shifting the focus from DNA to RNASemantic proximity Read ↗

Integration of genomic analysis and in vivo transfection to identify sprouty 2 as a candidate tumor suppressor in liver cancer†Semantic proximity Read ↗

Differential screening and suppression subtractive hybridization identified genes differentially expressed in an estrogen receptor-positive breast carcinoma cell line.Semantic proximity Read ↗

Genome-Wide Screening of Genes Showing Altered Expression in Liver Metastases of Human Colorectal Cancers by cDNA MicroarraySemantic proximity Read ↗

Comparative Gene Expression Analysis of Ovarian Carcinoma and Normal Ovarian Epithelium by Serial Analysis of Gene ExpressionSemantic proximity Read ↗

Identification and cloning of genes displaying elevated expression as a consequence of metastatic progression in human melanoma cells by rapid subtraction hybridizationSemantic proximity Read ↗

edgeR: a versatile tool for the analysis of shRNA-seq and CRISPR-Cas9 genetic screensSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.