Genetic structure of typical and atypical populations of Candida albicans from Africa.

doi:10.1006/fgbi.1999.1164

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Article

Genetic structure of typical and atypical populations of Candida albicans from Africa.

Fungal genetics and biology : FG & B - 1 Nov 1999

Forche A, Schönian G, Gräser Y, Vilgalys R, Mitchell T G

Abstract excerpt

Atypical isolates of the pathogenic yeast Candida albicans have been reported with increasing frequency. To investigate the origin of a set of atypical isolates and their relationship to typical isolates, we employed a combination of molecular phylogenetic and population genetic analyses using rDNA sequencing, PCR fingerprinting, and analysis of co-dominant DNA nucleotide polymorphisms to characterize the...

Topics

Africa
Candida albicans
Candidiasis
DNA Fingerprinting
Female
Genetic Markers
Genetic Variation
Heterozygote
Humans
Linkage Disequilibrium
Molecular Sequence Data
Phylogeny
Polymerase Chain Reaction
Polymorphism, Genetic
Polymorphism, Restriction Fragment Length
Polymorphism, Single-Stranded Conformational
Recombination, Genetic

Source

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Identifiers

PMID: 10587473
DOI: 10.1006/fgbi.1999.1164

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