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Article

Evidence that the product of the human X-linked CGD gene, gp91-phox, is a voltage-gated H(+) pathway.

The Journal of general physiology - 1 Dec 1999

Henderson L M, Meech R W

Abstract excerpt

Expression of gp91-phox in Chinese hamster ovary (CHO91) cells is correlated with the presence of a voltage-gated H(+) conductance. As one component of NADPH oxidase in neutrophils, gp91-phox is responsible for catalyzing the production of superoxide (O(2).(2)). Suspensions of CHO91 cells exhibit arachidonate-activatable H(+) fluxes (Henderson, L.M., G. Banting, and J.B. Chappell. 1995. J. Biol. Chem....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 10578014
DOI: 10.1085/jgp.114.6.771
PMCID: PMC2230652

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Evidence that the product of the human X-linked CGD gene, gp91-phox, is a voltage-gated H(+) pathway.PMID 10578014Read ↗

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Identification and functional characterization of two novel mutations in the α-helical loop (residues 484-503) of CYBB/gp91(phox) resulting in the rare X91(+) variant of chronic granulomatous disease.Semantic proximity Read ↗

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